Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961666 | 0.96 | TSHR (0.32) | TSHR | |
| SCHEMBL6968358 | 0.94 | TSHR (0.33) | TSHR | |
| SCHEMBL6965952 | 0.91 | — | — | |
| SCHEMBL6963253 | 0.85 | — | — | |
| SCHEMBL3577333 | 0.81 | TSHR (0.46) | TSHRTDP1L3MBTL1 | |
| SCHEMBL6967567 | 0.77 | PTPN1 (0.31) | — | |
| SCHEMBL5187673 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL3640258 | 0.71 | PTPN1 (0.46) | TSHRTDP1L3MBTL1 | |
| SCHEMBL6966305 | 0.70 | — | — | |
| SCHEMBL14563999 | 0.68 | HSD17B3 (0.36) | TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |