Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590618 | 0.90 | TSHR (0.38) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11801347 | 0.87 | KDM4E (0.36) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11801338 | 0.87 | KDM4E (0.36) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11801341 | 0.87 | KDM4E (0.36) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL3577333 | 0.83 | TSHR (0.46) | TSHRESR1CYP1A2LMNAMAPT | |
| SCHEMBL8947546 | 0.83 | TSHR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL28417053 | 0.83 | TSHR (0.48) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL6970357 | 0.82 | — | — | |
| SCHEMBL6966305 | 0.81 | — | — | |
| SCHEMBL43932 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569965-B1 | METHOD FOR RADICAL POLYMERISATION IN THE PRESENCE OF A CHAIN TRANSFER AGENT | BASF AG (DE) | 2007-07-11 | — | — | EP | claimed |
| US-7196150-B2 | Method for radical polymerisation in the presence of a chain transfer agent | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-27 | — | — | US | claimed |
| US-20060058478-A1 | Method for radical polymerisation in the presence of a chain transfer agent | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-16 | — | — | US | claimed |
| US-8163761-B2 | Methods and compositions for treating disorders | HYDRA BIOSCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-20120046305-A1 | METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISORDERS | ELI LILLY AND COMPANY | 2012-02-23 | — | — | US | disclosed |
| US-20090143377-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| CN-1307171-C | Benzopyrans and benzothiopyrans, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GMBH (DE) | 2007-03-28 | — | — | CN | disclosed |
| CN-1554651-A | Benzopyrans and benzothiopyrans, pharmaceutical compositions containing them and process for their preparation | Ĭ��ר���ɷ�����˾ | 2004-12-15 | — | — | CN | disclosed |
| CN-1173967-C | Benzopyran and benzoxepin *, pharmaceutical compositions containing them and process for preparing them | Ĭ��ר���ɷ�����˾ | 2004-11-03 | — | — | CN | disclosed |
| CN-1359383-A | Benzopyran and benzoxepin *, pharmaceutical compositions containing them and process for preparing them | MERCK PATENT GMBH (DE) | 2002-07-17 | — | — | CN | disclosed |
| US-5990122-A | SUBSTITUTED IN THE 7-POSITION BY A TRICYCLIC AMINE RADICAL; REDUCED GENOTOXIC PROPERTIES AND INCREASED ANTIBACTERIAL ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5986105-A | ENANTIOMORPHS AS BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-16 | — | — | US | disclosed |
| US-5753669-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-19 | — | — | US | disclosed |
| US-5605910-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| EP-0609289-B1 | IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UPJOHN CO (US) | 1996-07-17 | — | — | EP | disclosed |
| US-5442062-A | Treating hypertension, congestive heart failure | THE UPJOHN COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0540209-A1 | Imidazole derivatives and pharmaceutical compositions containing the same | THE UPJOHN COMPANY (US) | 1993-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143377-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | TSHR 3225/4885CA12 2010/4885CA1 1049/4885 |
| US-20120046305-A1 | METHODS AND COMPOSITIONS FOR TREATING RESPIRATORY DISORDERS | TRPA1, TRPV1, TRPV3 | TSHR 3294/4885CA12 1344/4885CA1 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.