Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971069 | 1.00 | PAM (0.63) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL8452840 | 0.83 | PAM (0.66) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL251039 | 0.82 | PAM (0.59) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL2877458 | 0.81 | CYP4F2 (0.64) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL28297670 | 0.81 | PAM (0.63) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL2877454 | 0.81 | CYP4F2 (0.64) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL28165805 | 0.81 | PAM (0.63) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL10891882 | 0.80 | PAM (0.61) | PAMMAOBCYP4F2CYP4A11LMNA | |
| SCHEMBL11765846 | 0.80 | PAM (0.61) | PAMMAOBIDO1CYP4F2CYP4A11 | |
| SCHEMBL10891880 | 0.80 | PAM (0.61) | PAMMAOBCYP4F2CYP4A11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |