Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.64 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.64 |
| ▸ | PAM | P19021 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877454 | 1.00 | CYP4F2 (0.64) | CYP4F2CYP4A11PAMMAOBMAOA | |
| SCHEMBL13908714 | 0.96 | CYP4F2 (0.65) | CYP4F2CYP4A11PAMMAOBMAOA | |
| Hydrazine SCHEMBL30778291 | 0.96 | CYP4F2 (0.60) | CYP4F2CYP4A11PAMMAOBMAOA | |
| Nitrogen SCHEMBL29159384 | 0.96 | CYP4F2 (0.60) | CYP4F2CYP4A11PAMMAOBMAOA | |
| SCHEMBL13908762 | 0.92 | CYP4F2 (0.60) | CYP4F2CYP4A11PAMMAOBMAOA | |
| SCHEMBL11274669 | 0.88 | CYP4F2 (0.51) | CYP4F2CYP4A11PAMMAOBALDH1A1 | |
| SCHEMBL11274670 | 0.88 | CYP4F2 (0.51) | CYP4F2CYP4A11PAMMAOBALDH1A1 | |
| SCHEMBL10891880 | 0.84 | PAM (0.61) | CYP4F2CYP4A11PAMMAOBMAOA | |
| SCHEMBL10891882 | 0.84 | PAM (0.61) | CYP4F2CYP4A11PAMMAOBMAOA | |
| SCHEMBL8452840 | 0.83 | PAM (0.66) | CYP4F2CYP4A11PAMMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050006246-A1 | Nitrogen atom transfer | YUDIN ANDREI K (CA) | 2005-01-13 | — | — | US | claimed |
| WO-2003010361-A2 | NITROGEN ATOM TRANSFER | YLEKTRA INC. (CA) | 2003-02-06 | — | — | WO | claimed |
| CN-119638540-A | Method for reducing alpha, beta-unsaturated ester, nitrile and amide | 南开大学 | 2025-03-18 | — | — | CN | disclosed |
| US-20240300974-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2024-09-12 | — | — | US | disclosed |
| EP-4397309-A2 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | F. Hoffmann-La Roche AG (CH) | 2024-07-10 | — | — | EP | disclosed |
| CN-117603152-A | Novel chiral binuclear rhodium complex and preparation method and application thereof | 肇庆学院 | 2024-02-27 | — | — | CN | disclosed |
| EP-3652178-B1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2024-01-24 | — | — | EP | disclosed |
| US-11834461-B2 | Bicyclic ketone compounds and methods of use thereof | GENENTECH, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20210139504-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2021-05-13 | — | — | US | disclosed |
| US-10975095-B2 | — | — | 2021-04-13 | — | — | US | disclosed |
| EP-3652178-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | H. Hoffnabb-La Roche Ag (CH) | 2020-05-20 | — | — | EP | disclosed |
| CN-100470366-C | Polymeric composition and lithographic printing platemaking forebody | FUJI PHOTO FILM CO LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| CN-101149562-A | Photosensitive composition, photosensitive film, permanent pattern forming method and printing circuit board | FUJIFILM CORP (JP) | 2008-03-26 | — | — | CN | disclosed |
| CN-101098697-A | Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor | CYTOKINE PHARMASCIENCES INC (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-1235089-C | Photosensitive lithographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2006-01-04 | — | — | CN | disclosed |
| US-20050006246-A1 | Nitrogen atom transfer | YUDIN ANDREI K (CA) | 2005-01-13 | — | — | US | disclosed |
| CN-1495524-A | Polymeric composition and lithographic printing platemaking forebody | 富士胶片株式会社 | 2004-05-12 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| WO-2003010361-A2 | NITROGEN ATOM TRANSFER | YLEKTRA INC. (CA) | 2003-02-06 | — | — | WO | disclosed |
| CN-1355448-A | Photosensitive lithographic printing plate | FUJI PHOTO FILM CO LTD (JP) | 2002-06-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139504-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | HSD17B7, CYP11B1, CYP11B2 | CYP4F2 99/4885CYP4A11 20/4885PAM 2261/4885 |
| US-10975095-B2 | — | CYP1B1, UGT1A1, CYP4B1 | CYP4F2 72/4885CYP4A11 17/4885PAM 3609/4885 |
| US-11834461-B2 | Bicyclic ketone compounds and methods of use thereof | HSD17B7, CYP11B1, CYP11B2 | CYP4F2 99/4885CYP4A11 20/4885PAM 2261/4885 |
| US-20240300974-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | HSD17B7, CYP11B1, CYP11B2 | CYP4F2 99/4885CYP4A11 20/4885PAM 2261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.