Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969784 | 0.85 | QPCT (0.54) | CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL6978774 | 0.82 | CYP19A1 (0.59) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6978364 | 0.78 | CYP19A1 (0.54) | CYP11B1CYP11B2CYP19A1HMOX1 | |
| SCHEMBL6971977 | 0.77 | HMOX1 (0.63) | CYP11B1CYP11B2CYP19A1HMOX1 | |
| SCHEMBL11284375 | 0.76 | CYP2A6 (0.65) | CYP11B1CYP11B2CYP19A1CYP3A4IDO1 | |
| SCHEMBL11284356 | 0.76 | CYP19A1 (0.63) | CYP11B1CYP11B2CYP19A1IDO1 | |
| SCHEMBL11286358 | 0.75 | CYP11B1 (0.61) | CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL411443 | 0.74 | HMOX1 (0.57) | CYP11B1CYP11B2CYP19A1HMOX1 | |
| SCHEMBL2830811 | 0.74 | APP (0.46) | IDO1 | |
| Hydrochloric Acid SCHEMBL410571 | 0.73 | HMOX1 (0.56) | CYP11B1CYP11B2CYP19A1HMOX1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | LES LABORATORIES SERVIER (FR) | 2003-10-23 | — | — | US | disclosed |
| CN-1445226-A | New cornpound derivated from quinazoline, itd preparation method and medicinal composite containig them | ADIR (FR) | 2003-10-01 | — | — | CN | disclosed |
| EP-1346992-A1 | Quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | NQO2, XDH, DRD1 | CYP11B1 162/4885CYP11B2 128/4885CYP19A1 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.