Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108225 | 0.85 | ALDH1A1 (0.90) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL7466468 | 0.84 | HPGD (0.71) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL786692 | 0.83 | ALDH1A1 (0.76) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL5970063 | 0.82 | HPGD (1.00) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL8145757 | 0.81 | HPGD (0.77) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL14140751 | 0.81 | HPGD (1.00) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL13486221 | 0.81 | HPGD (1.00) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL244547 | 0.81 | HPGD (1.00) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL9309209 | 0.81 | HPGD (0.65) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL3456555 | 0.80 | HSD17B10 (0.61) | ALDH1A1HPGDHSD17B10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5948786-A | BLOCKING TUMOR NECROSIS FACTOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-09-07 | — | — | US | disclosed |