Indole

Indole

SCHEMBL69715

c1ccc2[nH]ccc2c1.c1ccncc1

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.71
TRPA1 O75762 1/20 0.71
CA1 P00915 1/20 0.71
CA2 P00918 1/20 0.71
ITGB2 P05107 1/20 0.71
ICAM1 P05362 1/20 0.71
ITGAL P20701 1/20 0.71
CA4 P22748 1/20 0.71
CA6 P23280 1/20 0.71
ADK P55263 1/20 0.71
NPC1 O15118 1/20 0.46
PIK3CD O00329 1/20 0.42
AXL P30530 1/20 0.41
NUDT1 P36639 1/20 0.41
CYP17A1 P05093 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
ALDH1A1 P00352 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL31131470 1.00 AHR (0.71) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL28690779 1.00 AHR (0.71) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL27909376 1.00 AHR (0.71) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL28342343 0.98 AHR (0.68) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL28299852 0.98 AHR (0.68) AHRTRPA1CA1CA2ITGB2
Naphthalene SCHEMBL28144510 0.98 AHR (0.68) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL27393259 0.91 AHR (0.77) AHRTRPA1CA1CA2ITGB2
Carbazole SCHEMBL28161326 0.89 AHR (0.57) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL27752462 0.88 AHR (0.55) AHRTRPA1CA1CA2ITGB2
Indole SCHEMBL28150508 0.88 TRPA1 (0.55) AHRTRPA1CA1CA2ITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 768 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116973342-A Lysosome imaging probe 湖北科技学院 2023-10-31 CN claimed
CN-116789638-A Indolopyridine acid indicator, preparation method and application thereof 湖北科技学院 2023-09-22 CN claimed
CN-114213410-B Synthesis method of aromatic ring [ a ] carbazole compound and aromatic ring [ g ] pyridine indole compound 湖南师范大学 2023-03-14 CN claimed
CN-111398269-B Method for preparing PH test paper by indole pyridinium derivative 湖北科技学院 2023-03-03 CN claimed
CN-109790461-B Mixture, composition and organic electronic device 广州华睿光电材料有限公司 2022-08-12 CN claimed
CN-113214252-B Synthesis method of 6-phenyl-7- (pyridine-2-yl) -7H-indolo [2,3-c ] quinoline compound 常州大学 2022-02-11 CN claimed
CN-113956273-A Carbazole dimer and synthesis method and application thereof 南京艾姆材料科技有限公司 2022-01-21 CN claimed
US-11161933-B2 Conjugated polymer and use thereof in organic electronic device GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2021-11-02 US claimed
CN-113484317-A Method for preparing PH test paper through benzyl chloride pyridinium derivative 湖北科技学院 2021-10-08 CN claimed
CN-113214252-A Synthesis method of 6-phenyl-7- (pyridine-2-yl) -7H-indolo [2,3-c ] quinoline compound 常州大学 2021-08-06 CN claimed
CN-109791980-A Conjugated polymer and its application in organic electronic device 广州华睿光电材料有限公司 2019-05-21 CN claimed
CN-109790118-A Conjugated polymer and its application in organic electronic device 广州华睿光电材料有限公司 2019-05-21 CN claimed
CN-109761877-A A kind of organic compound and its organic electroluminescence device using the compound 宇瑞(上海)化学有限公司 2019-05-17 CN claimed
CN-109734648-A Organic electroluminescence device compound and its organic electroluminescence device for using the compound 宇瑞(上海)化学有限公司 2019-05-10 CN claimed
CN-107108862-A Conjugated polymers containing ethynyl crosslinking groups, mixtures, compositions, organic electronic devices comprising the same, and uses thereof 广州华睿光电材料有限公司 2017-08-29 CN claimed
CN-106478730-A Organometallic complex, light-emitting component, light-emitting device, electronic equipment and illuminator 株式会社半导体能源研究所 2017-03-08 CN claimed
CN-103265947-A Indolpyridine type fluorescent probe for imaging RNA and nucleolus in living cell UNIV SHANDONG 2013-08-28 CN claimed
CN-1914149-A Combination therapy for treating cyclooxygenase-2 mediated diseases or conditions in patients at risk of thrombotic cardiovascular events MERCK FROSST CANADA INC (CA) 2007-02-14 CN claimed
CN-1120166-C New class of benzoporphyrin derivative photoactive compounds UNIV BRITISH COLUMBIA (CA) 2003-09-03 CN claimed
CN-1255135-A New class of benzoporphyrin derivative photoactive compounds UNIV BRITISH COLUMBIA (CA) 2000-05-31 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161933-B2 Conjugated polymer and use thereof in organic electronic device PCBP1, PITPNB, ETFB AHR 3367/4885TRPA1 3630/4885CA1 4097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.