Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.76 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.76 |
| ▸ | OXTR | P30559 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972323 | 0.90 | AVPR2 (0.80) | AVPR2AVPR1AOXTR | |
| SCHEMBL6959177 | 0.89 | AVPR2 (0.62) | AVPR2AVPR1AOXTRALDH1A1TSHR | |
| SCHEMBL6967676 | 0.89 | AVPR2 (0.81) | AVPR2AVPR1AOXTR | |
| SCHEMBL7354099 | 0.88 | ALDH1A1 (0.80) | ALDH1A1TSHRMAPT | |
| SCHEMBL8961653 | 0.88 | AVPR2 (0.80) | AVPR2AVPR1AOXTR | |
| SCHEMBL6968619 | 0.87 | AVPR2 (0.79) | AVPR2AVPR1AOXTR | |
| SCHEMBL6955045 | 0.87 | AVPR2 (0.85) | AVPR2AVPR1AOXTR | |
| SCHEMBL6963965 | 0.87 | AVPR2 (0.72) | AVPR2AVPR1AOXTR | |
| SCHEMBL6958657 | 0.85 | AVPR2 (0.76) | AVPR2AVPR1AOXTR | |
| SCHEMBL6969873 | 0.85 | AVPR2 (0.73) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |