Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 7/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971488 | 0.90 | ADAMTS4 (0.39) | ADAMTS4MMP13ALDH1A1MAPTPTGES | |
| SCHEMBL6964408 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTNR3C1 | |
| SCHEMBL6969060 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTPTGESNR3C1 | |
| SCHEMBL6973145 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTNR3C1 | |
| SCHEMBL6972441 | 0.80 | ALDH1A1 (0.43) | ADAMTS4MMP13ALDH1A1MAPTNR3C1 | |
| SCHEMBL6968547 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTNR3C1 | |
| SCHEMBL6973013 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MAPTNR3C1 | |
| SCHEMBL6971108 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGESNR3C1 | |
| SCHEMBL6971104 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGESNR3C1 | |
| SCHEMBL6960549 | 0.76 | MAPT (0.38) | ALDH1A1MAPTNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |