Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PRCP | P42785 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714058 | 1.00 | MEN1 (0.60) | MEN1KMT2APRCPPOLBCTDSP1 | |
| SCHEMBL7315854 | 1.00 | MEN1 (0.60) | MEN1KMT2APRCPPOLBCTDSP1 | |
| SCHEMBL12310857 | 1.00 | MEN1 (0.60) | MEN1KMT2APRCPPOLBCTDSP1 | |
| SCHEMBL13479489 | 1.00 | MEN1 (0.60) | MEN1KMT2APRCPPOLBCTDSP1 | |
| SCHEMBL13205707 | 1.00 | MEN1 (0.60) | MEN1KMT2APRCPPOLBCTDSP1 | |
| SCHEMBL7315864 | 1.00 | MEN1 (0.60) | MEN1KMT2APRCPPOLBCTDSP1 | |
| SCHEMBL7311069 | 0.86 | LMNA (0.51) | MEN1KMT2APRCPLMNA | |
| SCHEMBL7318689 | 0.86 | LMNA (0.51) | MEN1KMT2APRCPLMNA | |
| SCHEMBL13479463 | 0.86 | CTRB1 (0.47) | MEN1KMT2APRCPPOLBCTDSP1 | |
| SCHEMBL12640063 | 0.85 | MEN1 (0.64) | MEN1KMT2APRCPPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |