Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962089 | 0.88 | — | — | |
| SCHEMBL6969333 | 0.88 | DHODH (0.33) | MAOAMAOBNOTUMHAO1KMT2A | |
| SCHEMBL6961492 | 0.86 | MAOA (0.36) | MAOAMAOBNOTUMHAO1NPSR1 | |
| SCHEMBL7087586 | 0.86 | MEN1 (0.45) | MAOAMAOBNOTUMMEN1KMT2A | |
| SCHEMBL6973797 | 0.86 | MAOA (0.38) | MAOAMAOBNOTUMHAO1ALDH1A1 | |
| SCHEMBL7087555 | 0.86 | GCGR (0.38) | MAOAMAOBNOTUMHAO1NPSR1 | |
| SCHEMBL6974087 | 0.85 | SMN1; SMN2 (0.35) | MAOAMAOBMEN1KMT2ANPSR1 | |
| SCHEMBL7081102 | 0.84 | GCGR (0.36) | MAOAMAOBNOTUMHAO1MEN1 | |
| SCHEMBL6968511 | 0.84 | MAOA (0.36) | MAOAMAOBNOTUMHAO1NPSR1 | |
| SCHEMBL6974959 | 0.84 | MAOA (0.36) | MAOAMAOBNOTUMHAO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |