Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 6/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 6/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503724 | 0.79 | PARP1 (0.62) | RAB9AFLT1FLT4KDRMEN1 | |
| SCHEMBL6970353 | 0.77 | S1PR2 (0.47) | RAB9AMEN1KMT2A | |
| SCHEMBL1987275 | 0.76 | ALDH1A1 (0.61) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL19089797 | 0.76 | TPMT (0.52) | RAB9ATPMTFLT1FLT4KDR | |
| SCHEMBL1003995 | 0.76 | TPMT (0.52) | RAB9ATPMTFLT1FLT4KDR | |
| SCHEMBL2635338 | 0.76 | KDM4E (0.61) | RAB9ATPMTFLT1FLT4KDR | |
| SCHEMBL24593859 | 0.73 | ATM (0.56) | RAB9ATPMTFLT1FLT4KDR | |
| SCHEMBL14060074 | 0.73 | TPMT (0.48) | RAB9ATPMTFLT1FLT4KDR | |
| SCHEMBL9732080 | 0.73 | TPMT (0.48) | RAB9ATPMTFLT1FLT4KDR | |
| SCHEMBL7151204 | 0.73 | ATM (0.56) | RAB9ATPMTFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |