Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505475 | 0.82 | TAS1R3 (0.56) | BCHEACHEKMT2ATAS1R3TAS1R1 | |
| SCHEMBL23060397 | 0.82 | S1PR2 (0.50) | S1PR2BCHEACHEMEN1KMT2A | |
| SCHEMBL6970356 | 0.78 | HPGD (0.47) | S1PR2BCHEACHEMEN1KMT2A | |
| SCHEMBL6402681 | 0.78 | KDM4E (0.52) | S1PR2BCHEACHEMEN1KMT2A | |
| SCHEMBL6971023 | 0.78 | BCHE (0.49) | S1PR2BCHEACHEMEN1KMT2A | |
| SCHEMBL16870259 | 0.78 | S1PR2 (0.42) | S1PR2BCHEACHEMEN1KMT2A | |
| SCHEMBL6971725 | 0.77 | RAB9A (0.55) | MEN1KMT2ARAB9A | |
| SCHEMBL6504213 | 0.76 | TAS1R3 (0.51) | SLC6A3KCNH2TAAR1TAS1R3TAS1R1 | |
| SCHEMBL8957220 | 0.75 | BCHE (0.50) | S1PR2BCHEACHEMEN1KMT2A | |
| SCHEMBL1591897 | 0.74 | POLB (0.46) | S1PR2BCHEACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |