Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAX | P61244 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | UBE2D3 | P61077 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264665 | 0.83 | HDAC1 (0.42) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL6422675 | 0.82 | MTOR (0.43) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL14022964 | 0.80 | HDAC1 (0.41) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL7451795 | 0.80 | TSHR (0.57) | HDAC1HDAC2GRM5ALDH1A1HCRTR1 | |
| SCHEMBL27629859 | 0.80 | MTOR (0.42) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL28766468 | 0.80 | IDO1 (0.41) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL29732178 | 0.80 | TSHR (0.57) | HDAC1HDAC2GRM5ALDH1A1HCRTR1 | |
| SCHEMBL27259089 | 0.80 | HDAC1 (0.41) | HDAC1HDAC2GRM5F2MTOR | |
| SCHEMBL281 | 0.80 | TSHR (0.57) | HDAC1HDAC2GRM5ALDH1A1HCRTR1 | |
| SCHEMBL28379117 | 0.78 | HDAC1 (0.40) | HDAC1HDAC2GRM5F2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |