SCHEMBL6971904

SCHEMBL6971904

N#CC1(NC(=O)C(N)CC2CCCCC2)CCNCC1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSS P25774 18/20 0.52
CTSL P07711 5/20 0.49
CTSC P53634 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5367945 0.99 CTSS (0.51) CTSSCTSLCTSC
SCHEMBL5363252 0.93 CTSS (0.60) CTSSCTSLCTSC
SCHEMBL5364783 0.85 CTSS (0.49) CTSSCTSLCTSC
SCHEMBL5361059 0.85 CTSS (0.60) CTSSCTSLCTSC
Hydrochloric Acid SCHEMBL5361278 0.84 CTSS (0.59) CTSSCTSLCTSC
SCHEMBL7075407 0.84 CTSS (0.45) CTSSCTSLCTSC
SCHEMBL7007715 0.83 CTSS (0.39) CTSSCTSLCTSC
SCHEMBL5356456 0.83 CTSS (0.62) CTSSCTSL
SCHEMBL5363867 0.82 CTSS (0.53) CTSSCTSL
Hydrochloric Acid SCHEMBL6349152 0.82 CTSS (0.61) CTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1218372-B1 NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES BOEHRINGER INGELHEIM PHARMA (US) 2003-07-02 EP claimed