Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.63 |
| ▸ | MMP3 | P08254 | 9/20 | 0.63 |
| ▸ | MMP9 | P14780 | 3/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | MMP14 | P50281 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6972622 | 0.93 | MMP2 (0.62) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6437469 | 0.92 | MMP2 (0.63) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6968408 | 0.92 | MMP2 (0.67) | MMP2MMP3MMP9MMP1MMP14 | |
| Hydrochloric Acid SCHEMBL6972714 | 0.91 | MMP2 (0.66) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6970701 | 0.91 | MMP2 (0.60) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6959909 | 0.89 | MMP2 (0.51) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6586243 | 0.89 | MMP2 (0.49) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6964268 | 0.88 | MMP2 (0.53) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6437467 | 0.87 | MMP2 (0.51) | MMP2MMP3MMP9MMP1MMP14 | |
| SCHEMBL6973195 | 0.87 | MMP2 (0.53) | MMP2MMP3MMP9MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |