SCHEMBL6971956

SCHEMBL6971956

CCCCc1nc(C)c(CC(N)=O)c(=O)n1Cc1ccc(-c2ccccc2)c(-c2nnn[nH]2)c1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.52
PPARG P37231 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6971961 0.91 PPARG (0.61) AGTR1PPARG
SCHEMBL9844109 0.91 AGTR1 (0.51) AGTR1PPARG
SCHEMBL17434766 0.89 AGTR1 (0.66) AGTR1PPARG
SCHEMBL8118527 0.88 AGTR1 (0.64) AGTR1
SCHEMBL9843811 0.87 AGTR1 (0.51) AGTR1PPARG
SCHEMBL8118430 0.87 AGTR1 (0.58) AGTR1
SCHEMBL7995129 0.86 AGTR1 (0.65) AGTR1PPARG
SCHEMBL8124840 0.86 AGTR1 (0.65) AGTR1PPARG
SCHEMBL7819440 0.86 PPARG (0.61) AGTR1PPARG
SCHEMBL6964925 0.84 AGTR1 (0.63) AGTR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991627-B1 PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME BORYUNG PHARM (KR) 2003-07-02 EP disclosed
US-6294542-B1 Pyrimidinone compounds, pharmaceutical compositions containing the compounds and the process for preparing the same BORYUNG PHARMACEUTICAL CO. LTD. (KR) 2001-09-25 US disclosed
EP-0991627-A1 PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME BORYUNG PHARMACEUTICAL CO., LTD. (KR) 2000-04-12 EP disclosed
WO-1999055681-A1 PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME BORYUNG PHARMACEUTICAL CO., LTD. (KR) 1999-11-04 WO disclosed