SCHEMBL6971961

SCHEMBL6971961

CCCCc1nc(C)c(CC(N)=O)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.61
AGTR1 P30556 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6964925 0.93 AGTR1 (0.63) PPARGAGTR1
SCHEMBL7819440 0.93 PPARG (0.61) PPARGAGTR1
SCHEMBL9843837 0.92 AGTR1 (0.59) PPARGAGTR1
SCHEMBL6971956 0.91 AGTR1 (0.52) PPARGAGTR1
SCHEMBL7820489 0.91 AGTR1 (0.64) PPARGAGTR1
SCHEMBL6959880 0.91 AGTR1 (0.58) PPARGAGTR1
SCHEMBL7810831 0.91 PPARG (0.68) PPARGAGTR1
SCHEMBL7818608 0.90 PPARG (0.57) PPARGAGTR1
SCHEMBL9844027 0.90 AGTR1 (0.58) PPARGAGTR1
SCHEMBL9843911 0.90 AGTR1 (0.58) PPARGAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991627-B1 PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME BORYUNG PHARM (KR) 2003-07-02 EP disclosed
US-6294542-B1 Pyrimidinone compounds, pharmaceutical compositions containing the compounds and the process for preparing the same BORYUNG PHARMACEUTICAL CO. LTD. (KR) 2001-09-25 US disclosed
EP-0991627-A1 PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME BORYUNG PHARMACEUTICAL CO., LTD. (KR) 2000-04-12 EP disclosed
WO-1999055681-A1 PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME BORYUNG PHARMACEUTICAL CO., LTD. (KR) 1999-11-04 WO disclosed