Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PRKDC | P78527 | 3/20 | 0.50 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473981 | 0.85 | MAPT (0.56) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL8431738 | 0.83 | SLC13A5 (0.52) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL15577925 | 0.81 | MAPT (0.52) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL5738297 | 0.81 | MAPT (0.54) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL12592356 | 0.79 | SMN1; SMN2 (0.51) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL2899040 | 0.79 | LMNA (0.56) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL10473259 | 0.78 | MAPT (0.49) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL270272 | 0.77 | MAPT (0.65) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC | |
| SCHEMBL10472739 | 0.77 | SLC2A1 (0.49) | MAPTLMNASMN1; SMN2ALDH1A1SLC13A5 | |
| SCHEMBL10473286 | 0.76 | SLC13A5 (0.49) | MAPTLMNASMN1; SMN2ALDH1A1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973756-B1 | THIODEPSIPEPTIDES FOR COMBATING ENDOPARASITES AND A METHOD FOR PRODUCING THE SAME | BAYER AG (DE) | 2003-03-26 | — | — | EP | disclosed |
| US-6265537-B1 | CYCLIC COMPOUNDS; NEMATOCIDES FOR HUMANS AND ANIMALS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-0973756-A1 | THIODEPSIPEPTIDES FOR COMBATING ENDOPARASITES AND A METHOD FOR PRODUCING THE SAME | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043965-A1 | THIODEPSIPEPTIDES FOR COMBATING ENDOPARASITES AND A METHOD FOR PRODUCING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-08 | — | — | WO | disclosed |