Sugi Predict

Sugi Predict / Compounds / SCHEMBL697215

SCHEMBL697215

SCHEMBL697215

CC(C)(C)OC(=O)CC(=O)C1CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BTK Q06187 1/20 0.38
▸ KMT2A Q03164 4/20 0.37
▸ EPHX1 P07099 1/20 0.36
▸ ALDH1A1 P00352 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ MAPT P10636 1/20 0.35
▸ DGAT1 O75907 1/20 0.34
▸ CHRM2 P08172 1/20 0.34
▸ CHRM1 P11229 1/20 0.34
▸ CHRM3 P20309 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ TSHR P16473 1/20 0.34
▸ EPHX2 P34913 1/20 0.34
▸ GAA P10253 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ PTPN2 P17706 1/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ PTPN6 P29350 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7552309 0.98 BTK (0.37) BTKKMT2AEPHX1ALDH1A1MEN1
SCHEMBL7795853 0.94 BTK (0.35) BTKKMT2AEPHX1ALDH1A1MEN1
SCHEMBL8494766 0.92 BTK (0.46) BTKKMT2AEPHX1ALDH1A1MEN1
SCHEMBL1334743 0.92 SMN1; SMN2 (0.43) BTKKMT2AEPHX1ALDH1A1MEN1
SCHEMBL16732424 0.91 SMN1; SMN2 (0.41) BTKKMT2AALDH1A1MEN1DGAT1
SCHEMBL16732426 0.91 SMN1; SMN2 (0.41) BTKKMT2AALDH1A1MEN1DGAT1
SCHEMBL29333106 0.90 EPHX1 (0.43) BTKKMT2AEPHX1ALDH1A1MEN1
SCHEMBL696158 0.87 RECQL (0.41) BTKKMT2AEPHX1ALDH1A1MEN1
SCHEMBL21994463 0.83 HPGD (0.57) KMT2AEPHX1ALDH1A1MEN1MAPT
SCHEMBL21995317 0.83 HPGD (0.43) KMT2AEPHX1ALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049419-A1 PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS GENZYME CORPORATION (US) 2025-03-06 — — WO disclosed
US-11053226-B2 KRAS G12C inhibitors and methods of using the same AMGEN INC. (US) 2021-07-06 — — US disclosed
US-20200165231-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC. 2020-05-28 — — US disclosed
US-10010554-B2 Fused pyrimidines as inhibitors of P97 complex CLEAVE BIOSCIENCES, INC. (US) 2018-07-03 — — US disclosed
US-10010554-B2 Fused pyrimidines as inhibitors of P97 complex CLEAVE BIOSCIENCES, INC. (US) 2018-07-03 — — US disclosed
EP-2875018-B1 FUSED PYRIMIDINES AS INHIBITORS OF p97 COMPLEX CLEAVE BIOSCIENCES INC (US) 2018-02-14 — — EP disclosed
US-20170258795-A1 FUSED PYRIMIDINES AS INHIBITORS OF P97 COMPLEX CLEAVE THERAPEUTICS, INC. 2017-09-14 — — US disclosed
US-20170258795-A1 FUSED PYRIMIDINES AS INHIBITORS OF P97 COMPLEX CLEAVE THERAPEUTICS, INC. 2017-09-14 — — US disclosed
US-20170258795-A1 FUSED PYRIMIDINES AS INHIBITORS OF P97 COMPLEX CLEAVE THERAPEUTICS, INC. 2017-09-14 — — US disclosed
EP-3208270-A1 FUSED PYRIMIDINES AS INHIBITORS OF P97 COMPLEX Cleave Biosciences, Inc. (US) 2017-08-23 — — EP disclosed
EP-0527037-A1 4-Benzoylisoxazole derivatives and their use as herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1993-02-10 — — EP disclosed
EP-0527036-A1 4-Benzoylisoxazole derivatives and their use as herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1993-02-10 — — EP disclosed
CN-1068567-A NEW HERBICIDES RHONE POULENC AGRICULTURE (GB) 1993-02-03 — — CN disclosed
EP-0524018-A1 Isoxazole herbicides RHONE-POULENC AGRICULTURE LTD. (GB) 1993-01-20 — — EP disclosed
CN-1061596-A 4-Benzoylisoxazole Derivatives RHONE POULENC AGRICULTURE (GB) 1992-06-03 — — CN disclosed
EP-0487357-A1 4 Benzoyl isoxazole derivatives RHONE-POULENC AGRICULTURE LTD. (GB) 1992-05-27 — — EP disclosed
CN-1058777-A Different  oxazole derivatives RHONE POULENC AGRICULTURE (GB) 1992-02-19 — — CN disclosed
EP-0470856-A1 Isoxazole derivatives, process for their preparation and their herbicidal applications RHONE-POULENC AGRICULTURE LTD. (GB) 1992-02-12 — — EP disclosed
CN-1050188-A ISOXAZOLES HERBICIDES RHONE POULENC AGRICULTURE (GB) 1991-03-27 — — CN disclosed
EP-0418175-A2 Isoxazoles herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1991-03-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170258795-A1 FUSED PYRIMIDINES AS INHIBITORS OF P97 COMPLEX PSMG3, PSME1, PSMB1 BTK 3424/4885KMT2A 3080/4885EPHX1 1698/4885
US-11053226-B2 KRAS G12C inhibitors and methods of using the same KRAS, NRAS, HRAS BTK 3723/4885KMT2A 2069/4885EPHX1 1423/4885
US-20200165231-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME KRAS, NRAS, HRAS BTK 3723/4885KMT2A 2069/4885EPHX1 1423/4885
US-10010554-B2 Fused pyrimidines as inhibitors of P97 complex PSMG3, PSME1, PSMB1 BTK 3424/4885KMT2A 3080/4885EPHX1 1698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.