Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL748190 | 0.74 | CCR1 (0.50) | NFE2L2RAB9AALDH1A1CCR1CCR5 | |
| SCHEMBL30529332 | 0.74 | CCR1 (0.50) | NFE2L2RAB9AALDH1A1CCR1CCR5 | |
| SCHEMBL2847656 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CCR1CCR5CCR8MAPT | |
| Formic Acid Methyl Ester SCHEMBL27958624 | 0.71 | CCR4 (0.34) | NFE2L2CCR4ALDH1A1CCR1CCR5 | |
| SCHEMBL30320423 | 0.68 | DYRK1A (0.40) | CCR4GAAPKMRAB9AALDH1A1 | |
| SCHEMBL1662248 | 0.68 | DYRK1A (0.40) | CCR4GAAPKMRAB9AALDH1A1 | |
| SCHEMBL845897 | 0.68 | HPGD (0.37) | GAAPKMRAB9AALDH1A1CCR1 | |
| SCHEMBL845896 | 0.68 | HPGD (0.37) | GAAPKMRAB9AALDH1A1CCR1 | |
| SCHEMBL10707745 | 0.67 | L3MBTL1 (0.42) | NFE2L2RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL1534512 | 0.67 | CA1 (0.46) | NFE2L2GAAPKMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |