Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.58 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.58 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520785 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1HPGDGAA | |
| SCHEMBL13116725 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAALDH1A1HPGDGAA | |
| SCHEMBL27697974 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAALDH1A1HPGDGAA | |
| SCHEMBL28355041 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAALDH1A1HPGDGAA | |
| SCHEMBL13702282 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAALDH1A1HPGDGAA | |
| SCHEMBL13116736 | 0.83 | LMNA (0.53) | SMN1; SMN2LMNAALDH1A1HPGDPOLB | |
| SCHEMBL28354844 | 0.83 | KMT2A (0.66) | SMN1; SMN2LMNAALDH1A1HPGDPOLB | |
| SCHEMBL920392 | 0.83 | NSD2 (0.66) | SMN1; SMN2LMNAALDH1A1HPGDEGLN1 | |
| SCHEMBL30646753 | 0.82 | EGLN1 (0.57) | SMN1; SMN2LMNAALDH1A1HPGDEGLN1 | |
| SCHEMBL29065192 | 0.82 | EGLN1 (0.57) | SMN1; SMN2LMNAALDH1A1HPGDEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095036-B1 | CINNAMIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH THERAPEUTICS LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-6465471-B1 | INHIBIT BINDING OF ALPHA 4 INTEGRINS TO THEIR LIGANDS THUS THEY ARE OF USE IN PROPHYLAXIS AND TREATMENT OF IMMUNE OR INFLAMMATORY DISORDERS | CELLTECH THERAPEUTICS LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |
| EP-1095036-A1 | CINNAMIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001690-A1 | CINNAMIC ACID DERIVATIVES AS CELL ADHESION MOLECULES | CELLTECH THERAPEUTICS LIMITED (GB) | 2000-01-13 | — | — | WO | disclosed |