Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646753 | 1.00 | EGLN1 (0.57) | EGLN1FTOEGLN2GAAKEAP1 | |
| SCHEMBL31299772 | 0.94 | EGLN1 (0.52) | EGLN1FTOEGLN2GAAKEAP1 | |
| SCHEMBL6972329 | 0.82 | SMN1; SMN2 (0.61) | EGLN1FTOEGLN2GAALMNA | |
| SCHEMBL30267808 | 0.82 | CHIA (0.55) | NSD2LMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7382937 | 0.78 | EGLN1 (0.74) | EGLN1FTOEGLN2GAALMNA | |
| SCHEMBL13266784 | 0.78 | KDM4E (0.47) | GAALMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8883374 | 0.77 | FTO (0.69) | EGLN1FTOEGLN2GAAKDM4E | |
| SCHEMBL31448014 | 0.77 | KEAP1 (0.62) | EGLN1FTOEGLN2GAAKEAP1 | |
| SCHEMBL9569279 | 0.76 | GAA (0.47) | GAALMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL1721551 | 0.76 | P2RX7 (0.45) | ALDH1A1HPGDKMT2AP2RX7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12491146-B1 | Skin brightening compositions with thiopyridinone compound | L'OREAL (FR) | 2025-12-09 | — | — | US | claimed |
| CN-119775202-A | Synthesis method of 2-mercaptonicotinoyl glycine | 河南旭瑞新材料科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119174710-A | Melasyl formula for effectively whitening and improving skin color | 广州光华商贸有限公司 | 2024-12-24 | — | — | CN | claimed |
| CN-116687793-A | Use of myristyl nicotinate in cosmetics | 杭州睿研前瞻生物科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116549324-A | Composition containing nicotinamide ethyl retinoic acid ester and preparation method thereof | 杭州睿研前瞻生物科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| WO-2026098878-A1 | PERSONAL CARE CONCENTRATE COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2026-05-15 | — | — | WO | disclosed |
| WO-2026087117-A1 | PERSONAL CARE COMPOSITION BASED ON CARBOXYMETHYL CYSTEINE COMPOUND AND ACETYL METHIONINE COMPOUND | UNILEVER IP HOLDINGS B.V. (NL) | 2026-04-30 | — | — | WO | disclosed |
| WO-2026087156-A1 | PERSONAL CARE COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2026-04-30 | — | — | WO | disclosed |
| WO-2026087109-A1 | PERSONAL CARE COMPOSITION BASED ON AN ACETYL AMINOACID COMPOUND AND A CYSTINE COMPOUND | UNILEVER IP HOLDINGS B.V. (NL) | 2026-04-30 | — | — | WO | disclosed |
| CN-121735839-A | Preparation method of 2-mercaptonicotinoyl glycine | 珠海维羿医药科技有限公司 | 2026-03-27 | — | — | CN | disclosed |
| CN-121735839-A | Preparation method of 2-mercaptonicotinoyl glycine | 珠海维羿医药科技有限公司 | 2026-03-27 | — | — | CN | disclosed |
| US-12491146-B1 | Skin brightening compositions with thiopyridinone compound | L'OREAL (FR) | 2025-12-09 | — | — | US | disclosed |
| CN-119775202-A | Synthesis method of 2-mercaptonicotinoyl glycine | 河南旭瑞新材料科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119775202-A | Synthesis method of 2-mercaptonicotinoyl glycine | 河南旭瑞新材料科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119730829-A | Stabilization of thiopyridone compounds and compositions comprising the same | 莱雅公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119421698-A | Stabilization of thiopyridone compounds and compositions comprising the same | 莱雅公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119174710-A | Melasyl formula for effectively whitening and improving skin color | 广州光华商贸有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-119174710-A | Melasyl formula for effectively whitening and improving skin color | 广州光华商贸有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-116687793-A | Use of myristyl nicotinate in cosmetics | 杭州睿研前瞻生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116549324-A | Composition containing nicotinamide ethyl retinoic acid ester and preparation method thereof | 杭州睿研前瞻生物科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12491146-B1 | Skin brightening compositions with thiopyridinone compound | GLMN, GNMT, GLA | EGLN1 3390/4885FTO 2198/4885EGLN2 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.