Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972370 | 0.66 | S1PR1 (0.36) | S1PR1KCNA5LRRK2 | |
| SCHEMBL28579957 | 0.64 | ALDH1A1 (0.50) | GRM5 | |
| SCHEMBL28971616 | 0.62 | ALDH1A1 (0.52) | S1PR1IDO1GRM5 | |
| SCHEMBL171405 | 0.62 | IDO1 (0.59) | LRRK2ROCK2IDO1MAOBFLT3 | |
| SCHEMBL29467167 | 0.61 | HRH3 (0.55) | ROCK2IDO1ROCK1 | |
| SCHEMBL22968664 | 0.61 | HRH3 (0.55) | ROCK2IDO1ROCK1 | |
| SCHEMBL28971594 | 0.61 | S1PR1 (0.40) | S1PR1KCNA5 | |
| Hydrochloric Acid SCHEMBL29271375 | 0.60 | HRH3 (0.54) | ROCK2IDO1ROCK1 | |
| Hydrochloric Acid SCHEMBL30986706 | 0.60 | HRH3 (0.54) | ROCK2IDO1ROCK1 | |
| SCHEMBL22435570 | 0.60 | GLA (0.44) | S1PR1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |