Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528957 | 0.84 | ELANE (0.60) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL692280 | 0.82 | PTGES2 (0.55) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL122293 | 0.82 | SLC22A12 (0.48) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL29520001 | 0.82 | SLC22A12 (0.48) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL2646108 | 0.82 | ALPL (0.46) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL645001 | 0.82 | ALPL (0.46) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL6039108 | 0.82 | SLC22A12 (0.48) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL10646541 | 0.82 | SLC22A12 (0.48) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL29469931 | 0.82 | PTGES2 (0.55) | ALPLSLC22A12SLC40A1PTGES2HTR6 | |
| SCHEMBL6627180 | 0.81 | ELANE (0.47) | ALPLSLC22A12HTR6ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |