Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520001 | 1.00 | SLC22A12 (0.48) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL10952200 | 0.85 | ELANE (0.38) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL7865867 | 0.84 | TRPV4 (0.41) | SLC22A12ALPLSLC40A1PTGES2ELANE | |
| SCHEMBL3528957 | 0.82 | ELANE (0.60) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL6972429 | 0.82 | ALPL (0.47) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL16835442 | 0.82 | ELANE (0.36) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL645001 | 0.81 | ALPL (0.46) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL692280 | 0.81 | PTGES2 (0.55) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL10646541 | 0.81 | SLC22A12 (0.48) | SLC22A12ALPLSLC40A1PTGES2HTR6 | |
| SCHEMBL2646108 | 0.81 | ALPL (0.46) | SLC22A12ALPLSLC40A1PTGES2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478498-B | Silybin derivative or pharmaceutically acceptable salt thereof and application thereof | 柳州市工人医院 | 2024-04-02 | — | — | CN | claimed |
| CN-117185967-A | Preparation method of 2-trifluoromethoxybenzene sulfonamide | 大连奇凯医药科技有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-109608369-B | Sulfonyl ester group anthraquinone derivative and preparation method and application thereof | 广西大学 | 2021-04-09 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-12391680-B2 | Compounds and compositions for the treatment of cystic fibrosis | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-08-19 | — | — | US | disclosed |
| EP-3728194-B1 | QUINOLINE SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS | OTAGO INNOVATION LTD (NZ) | 2025-06-04 | — | — | EP | disclosed |
| US-20250171463-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. | 2025-05-29 | — | — | US | disclosed |
| CN-119462588-A | Flavone derivative containing sulfonamide structure and preparation method and application thereof | 上海中医药大学附属曙光医院 | 2025-02-18 | — | — | CN | disclosed |
| WO-2024238872-A2 | ISOINDOLINONE-GLUTARIMIDE ANTIBODY CONJUGATES, AND USES THEREOF | FIREFLY BIO, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-4433474-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2024-09-25 | — | — | EP | disclosed |
| US-12091406-B2 | Lysine acetyltransferase 6A (KAT6A) inhibitors and uses thereof | INSILICO MEDICINE IP LIMITED (HK) | 2024-09-17 | — | — | US | disclosed |
| CN-118063450-A | Arylsulfonamide compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-05-24 | — | — | CN | disclosed |
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0419831-A2 | Substituted sulfonylaminoazoles | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| US-4988381-A | HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0355385-A1 | Substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4732711-A | CORRESPONDING SULFONYLISOLYANATE AND THIOISOCYANATE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-22 | — | — | US | disclosed |
| US-4725304-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-02-16 | — | — | US | disclosed |
| EP-0173312-A1 | 1-(2-Trifluoromethoxy-phenylsulfonyl)-3-heteroaryl-(thio) ureas | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173318-A1 | Fluoralkoxyphenylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12091406-B2 | Lysine acetyltransferase 6A (KAT6A) inhibitors and uses thereof | KAT6A, KAT2A, KAT6B | SLC22A12 3495/4885ALPL 3720/4885SLC40A1 2947/4885 |
| US-20250171463-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | EBPL, EBP, CREBBP | SLC22A12 2080/4885ALPL 2941/4885SLC40A1 1409/4885 |
| US-12391680-B2 | Compounds and compositions for the treatment of cystic fibrosis | CFTR, ABCB11, ABCC5 | SLC22A12 132/4885ALPL 2756/4885SLC40A1 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.