Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | P4HB | P07237 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650287 | 0.85 | GSK3B (0.59) | GSK3BTYMSGRM5P4HBCLK1 | |
| SCHEMBL5652160 | 0.85 | GSK3B (0.59) | GSK3BTYMSGRM5P4HBCLK1 | |
| SCHEMBL30444713 | 0.82 | MRGPRX4 (0.56) | GSK3BGRM5P4HBMRGPRX4 | |
| SCHEMBL60040 | 0.82 | MRGPRX4 (0.56) | GSK3BGRM5P4HBMRGPRX4 | |
| SCHEMBL17460156 | 0.82 | GSK3B (0.56) | GSK3BTYMSGRM5P4HBCLK1 | |
| SCHEMBL10987144 | 0.81 | GSK3B (0.55) | GSK3BTYMSGRM5CLK1DYRK1A | |
| SCHEMBL7656344 | 0.81 | F2 (0.59) | GSK3BTYMSGRM5CLK1DYRK1A | |
| SCHEMBL5652166 | 0.81 | GSK3B (0.54) | GSK3BTYMSGRM5VNN1IRAK4 | |
| SCHEMBL2500188 | 0.79 | GSK3B (0.61) | GSK3BGRM5P4HBCLK1DYRK1A | |
| SCHEMBL31384418 | 0.79 | GSK3B (0.57) | GSK3BTYMSGRM5VNN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |