Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | USP5 | P45974 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636921 | 0.78 | RAB9A (0.57) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL29723028 | 0.76 | ACVR1 (0.61) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL122167 | 0.76 | ACVR1 (0.61) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL3190592 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL258690 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL30743619 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL28248362 | 0.76 | RAB9A (0.56) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL16181504 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL22021641 | 0.76 | KDM4E (0.54) | KDM4EHPGDHSD17B10RAB9ANPC1 | |
| SCHEMBL25101164 | 0.76 | KDM4E (0.50) | KDM4EHPGDHSD17B10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |