Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | BRD2 | P25440 | 3/20 | 0.50 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972668 | 1.00 | GFER (0.70) | GFERNPSR1LMNASMN1; SMN2PTGDR2 | |
| SCHEMBL6972662 | 1.00 | GFER (0.70) | GFERNPSR1LMNASMN1; SMN2PTGDR2 | |
| SCHEMBL4127182 | 0.83 | NPSR1 (1.00) | GFERNPSR1LMNASMN1; SMN2PTGDR2 | |
| SCHEMBL4127184 | 0.83 | NPSR1 (1.00) | GFERNPSR1LMNASMN1; SMN2PTGDR2 | |
| SCHEMBL221987 | 0.79 | BRD4 (0.74) | GFERNPSR1LMNASMN1; SMN2BRD4 | |
| SCHEMBL4126285 | 0.79 | BRD4 (0.74) | GFERNPSR1LMNASMN1; SMN2BRD4 | |
| SCHEMBL5836704 | 0.79 | BRD4 (0.74) | GFERNPSR1LMNASMN1; SMN2BRD4 | |
| SCHEMBL4122671 | 0.79 | BRD4 (0.74) | GFERNPSR1LMNASMN1; SMN2BRD4 | |
| SCHEMBL4129055 | 0.79 | BRD4 (0.74) | GFERNPSR1LMNASMN1; SMN2BRD4 | |
| SCHEMBL6983303 | 0.78 | LMNA (0.54) | GFERNPSR1LMNABRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216398-A1 | Soluble beta amyloid precursor protein secretion promoters | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1283055-A1 | SOLUBLE BETA AMYLOID PRECURSOR PROTEIN SECRETION PROMOTERS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216398-A1 | Soluble beta amyloid precursor protein secretion promoters | APP, BDNF, BACE1 | GFER 1016/4885NPSR1 541/4885LMNA 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.