Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606440 | 0.78 | SMN1; SMN2 (0.43) | RAB9APOLBSMN1; SMN2TNIKALDH1A1 | |
| SCHEMBL1773863 | 0.77 | RAB9A (0.61) | RAB9APOLBSMN1; SMN2L3MBTL1TNIK | |
| SCHEMBL28282909 | 0.74 | RAB9A (0.57) | RAB9APOLBSMN1; SMN2L3MBTL1TNIK | |
| SCHEMBL4893890 | 0.74 | RAB9A (0.57) | RAB9APOLBSMN1; SMN2L3MBTL1TNIK | |
| SCHEMBL20465066 | 0.73 | NOTUM (0.51) | RAB9APOLBSMN1; SMN2ALDH1A1NPC1 | |
| Boric Acid SCHEMBL8816030 | 0.71 | RAB9A (0.53) | RAB9APOLBSMN1; SMN2L3MBTL1TNIK | |
| SCHEMBL3834174 | 0.71 | MAPT (0.52) | RAB9APOLBSMN1; SMN2HPGDSALDH1A1 | |
| SCHEMBL23927532 | 0.71 | ADORA2A (0.38) | RAB9AL3MBTL1ALDH1A1NPC1MAPT | |
| SCHEMBL2386931 | 0.71 | SCN4A (0.61) | RAB9APOLBSMN1; SMN2HPGDSALDH1A1 | |
| SCHEMBL12948535 | 0.70 | POLB (0.39) | RAB9APOLBSMN1; SMN2L3MBTL1TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |