Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.52 |
| ▸ | RELA | Q04206 | 4/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888588 | 0.84 | RAB9A (0.65) | MAPTALOX15MEN1KMT2AHPGD | |
| SCHEMBL2113306 | 0.75 | CYP2A6 (0.58) | HPGDSMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL2659870 | 0.72 | HSD17B10 (0.53) | MAPTALOX15MEN1KMT2AHPGD | |
| SCHEMBL6972677 | 0.71 | RAB9A (0.38) | MAPTHPGDSMN1; SMN2HSD17B10RAB9A | |
| SCHEMBL10357571 | 0.69 | MEN1 (1.00) | MAPTALOX15MEN1KMT2AHPGD | |
| SCHEMBL10358211 | 0.69 | MAPT (0.68) | MAPTALOX15MEN1KMT2AHPGD | |
| SCHEMBL1528459 | 0.69 | ALDH1A1 (0.68) | MAPTALOX15MEN1KMT2AHPGD | |
| SCHEMBL31324688 | 0.67 | ALPL (0.57) | MAPTALOX15MEN1KMT2AHPGD | |
| SCHEMBL3499089 | 0.67 | ALPL (0.57) | MAPTALOX15MEN1KMT2AHPGD | |
| SCHEMBL2614354 | 0.67 | NPC1 (0.64) | MAPTALOX15MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146343-A1 | NOVEL SUBSTITUTED PYRAZOLES, 1,2,4-OXADIAZOLES, AND 1,3,4-OXADIAZOLES | MERCK & CO., INC. (US) | 2009-12-03 | — | — | WO | claimed |