Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972692 | 1.00 | PTGS1 (0.36) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL6967726 | 0.85 | PTGS1 (0.31) | PTGS1 | |
| SCHEMBL6967723 | 0.85 | PTGS1 (0.31) | PTGS1 | |
| SCHEMBL15121261 | 0.83 | ALDH1A1 (0.46) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL14775231 | 0.83 | ALDH1A1 (0.46) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL6967052 | 0.82 | — | — | |
| SCHEMBL6967047 | 0.82 | — | — | |
| SCHEMBL6958509 | 0.78 | FFAR1 (0.31) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL6958514 | 0.78 | FFAR1 (0.31) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL13455428 | 0.77 | PTGS1 (0.39) | PTGS1NR1I2PGRADORA3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |