SCHEMBL6958509

SCHEMBL6958509

CC/C=C/OC(=O)O[C]=O

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
CYP19A1 P11511 1/20 0.31
RXRA P19793 1/20 0.31
PPARG P37231 1/20 0.31
OXER1 Q8TDS5 1/20 0.31
PTGS1 P23219 1/20 0.30
NR1I2 O75469 1/20 0.30
PGR P06401 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
PTGS2 P35354 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6958514 1.00 FFAR1 (0.31) FFAR1ALDH1A1MAPTCYP19A1RXRA
SCHEMBL6973671 0.84 TAS1R3 (0.30)
SCHEMBL6973668 0.84 TAS1R3 (0.30)
SCHEMBL153167 0.82 ALDH1A1 (0.38) FFAR1ALDH1A1MAPTCYP19A1RXRA
SCHEMBL1598830 0.82 ALDH1A1 (0.38) FFAR1ALDH1A1MAPTCYP19A1RXRA
SCHEMBL6955242 0.81 F7 (0.38) FFAR1ALDH1A1MAPTCYP19A1PPARG
SCHEMBL6955239 0.81 F7 (0.38) FFAR1ALDH1A1MAPTCYP19A1PPARG
SCHEMBL10583137 0.78 ALDH1A1 (0.35) FFAR1ALDH1A1MAPTCYP19A1RXRA
SCHEMBL6972694 0.78 PTGS1 (0.36) FFAR1ALDH1A1MAPTCYP19A1RXRA
SCHEMBL6972692 0.78 PTGS1 (0.36) FFAR1ALDH1A1MAPTCYP19A1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed