SCHEMBL6972824

SCHEMBL6972824

CCCC(=O)NC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28683548 0.97 HDAC3 (0.52)
SCHEMBL1643947 0.85 HDAC3 (0.63)
SCHEMBL7356376 0.84 ALDH1A1 (0.53)
Water SCHEMBL29155573 0.82 HDAC3 (0.60)
SCHEMBL1285375 0.82 HSP90AA1 (0.58)
SCHEMBL25330155 0.80 HSP90AA1 (0.61)
SCHEMBL12700294 0.80 HSP90AA1 (0.61)
SCHEMBL6274637 0.80 HSP90AA1 (0.61)
SCHEMBL3190449 0.80 HSP90AA1 (0.61)
SCHEMBL14405350 0.80 HSP90AA1 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7303483-A None JP disclosed
CN-117561072-A Pharmaceutical compositions containing GLP-1 compounds 甘李药业股份有限公司 2024-02-13 CN disclosed
CN-114040889-A Graphene/graphene oxide core/shell particles and methods of making and using the same 堪萨斯州立大学研究基金会 2022-02-11 CN disclosed
US-20180105547-A1 METHODS FOR THE TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES CHILDREN'S MEDICAL CENTER CORPORATION (US) 2018-04-19 US disclosed
CN-107033164-A Prepare the synthetic method of ecteinascidin compounds 法马马有限公司 2017-08-11 CN disclosed
US-9657046-B2 Methods for the treatment and prevention of inflammatory diseases CHILDREN'S MEDICAL CENTER CORPORATION (US) 2017-05-23 US disclosed
US-20140301996-A1 METHODS FOR THE TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES UNIVERSITY OF BIRMINGHAM (GB) 2014-10-09 US disclosed
US-8580975-B2 Synthesis of macrocyclic cancer chemotherapy agents and methods of use PURDUE RESEARCH FOUNDATION (US) 2013-11-12 US disclosed
CN-103038240-A Synthetic method for preparing ecteinascidin compounds PHARMA MAR SA 2013-04-10 CN disclosed
US-20110028540-A1 SYNTHESIS OF MACROCYCLIC CANCER CHEMOTHERAPY AGENTS AND METHODS OF USE PURDUE RESEARCH FOUNDATION 2011-02-03 US disclosed
US-4160095-A PROSTAGLANDINS; ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1979-07-03 US disclosed
US-4157441-A PROSTAGLANDINS, ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1979-06-05 US disclosed
US-4151351-A PROSTAGLANDINS, ANTIINFLAMMATORY THE UPJOHN COMPANY (US) 1979-04-24 US disclosed
US-4131738-A 6-Hydroxy-PGE1 compounds THE UPJOHN COMPANY (US) 1978-12-26 US disclosed
US-4128713-A 6,7-Didehydro-PGI1 compounds THE UPJOHN COMPANY (US) 1978-12-05 US disclosed
US-4126744-A PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4112224-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1978-09-05 US disclosed
US-4109082-A PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS THE UPJOHN COMPANY (US) 1978-08-22 US disclosed
US-4100192-A Inter-phenylene-PG amides THE UPJOHN COMPANY (US) 1978-07-11 US disclosed
US-4097489-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-06-27 US disclosed