Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484667 | 0.62 | LMNA (0.54) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL3404878 | 0.62 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL137400 | 0.61 | KDM4E (0.56) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16293655 | 0.61 | KDM4E (0.52) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4723016 | 0.61 | KDM4E (0.52) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29888844 | 0.60 | SLC6A4 (0.56) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3696560 | 0.60 | SLC6A4 (0.56) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31288205 | 0.60 | KDM4E (0.56) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3991296 | 0.60 | KDM4E (0.56) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1990376 | 0.60 | KDM4E (0.56) | POLBMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |