Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 10/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974115 | 0.92 | GRIN1 (0.38) | GRIN1GRIN2BS1PR3KDM4ETLR7 | |
| SCHEMBL7078209 | 0.92 | S1PR3 (0.34) | GRIN1GRIN2BS1PR3KDM4EALOX5AP | |
| SCHEMBL6967980 | 0.90 | GRIN1 (0.39) | GRIN1GRIN2BS1PR3KDM4ESLC6A9 | |
| SCHEMBL6965115 | 0.89 | TLR7 (0.36) | GRIN1GRIN2BALOX5APTLR7 | |
| SCHEMBL6966820 | 0.89 | GRIN1 (0.38) | GRIN1GRIN2BS1PR3KDM4ESLC6A9 | |
| SCHEMBL6970143 | 0.89 | GRIN1 (0.38) | GRIN1GRIN2BS1PR3KDM4E | |
| SCHEMBL6973313 | 0.89 | GRIN1 (0.38) | GRIN1GRIN2BS1PR3KDM4ESLC6A9 | |
| SCHEMBL6962202 | 0.88 | GRM5 (0.38) | GRIN1GRIN2BKDM4EALOX5APNOX4 | |
| SCHEMBL7078156 | 0.88 | GRIN1 (0.36) | GRIN1GRIN2BS1PR3 | |
| SCHEMBL6960568 | 0.88 | GRIN1 (0.37) | GRIN1GRIN2BS1PR3KDM4EALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |