Sugi Predict

Sugi Predict / Compounds / SCHEMBL6973030

SCHEMBL6973030

SCHEMBL6973030

CCOC(=O)c1coc(/C(N)=N/O)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.44
▸ ALDH1A1 P00352 6/20 0.41
▸ MAPT P10636 3/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ NLRP3 Q96P20 1/20 0.41
▸ FBP1 P09467 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ KDM4E B2RXH2 5/20 0.36
▸ HPGD P15428 3/20 0.36
▸ HTT P42858 2/20 0.36
▸ RECQL P46063 1/20 0.36
▸ GAA P10253 3/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ POLB P06746 2/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ DAGLA Q9Y4D2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2227612 1.00 CYP1A2 (0.44) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL2227616 1.00 CYP1A2 (0.44) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL31412793 0.83 CYP1A2 (0.53) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL856245 0.80 CYP1A2 (0.50) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL13731319 0.78 CYP1A2 (0.47) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL2225941 0.77 CYP1A2 (0.44) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL479860 0.75 FBP1 (0.65) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL2070169 0.75 CYP1A2 (0.55) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL31396833 0.74 CYP1A2 (0.46) CYP1A2ALDH1A1MAPTNPC1RAB9A
SCHEMBL160214 0.73 CYP1A2 (0.53) CYP1A2ALDH1A1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2533783-B1 COMPOUNDS AND METHODS for the inhibition of HDAC TEMPERO PHARMACEUTICALS INC (US) 2015-11-04 — — EP disclosed
US-20150038534-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. 2015-02-05 — — US disclosed
US-20150038534-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. 2015-02-05 — — US disclosed
US-8901156-B2 Compounds and methods TEMPERO PHARMACEUTICALS, INC. (US) 2014-12-02 — — US disclosed
US-8901156-B2 Compounds and methods TEMPERO PHARMACEUTICALS, INC. (US) 2014-12-02 — — US disclosed
US-20130059883-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. 2013-03-07 — — US disclosed
US-20130059883-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. 2013-03-07 — — US disclosed
WO-2011088181-A9 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. (US) 2013-01-31 — — WO disclosed
WO-2011088181-A1 COMPOUNDS AND METHODS TEMPERO PHARMACEUTICALS, INC. (US) 2011-07-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150038534-A1 COMPOUNDS AND METHODS XDH, LPXN, CCNY CYP1A2 179/4885ALDH1A1 1152/4885MAPT 4479/4885
US-20130059883-A1 COMPOUNDS AND METHODS XDH, LPXN, CCNY CYP1A2 179/4885ALDH1A1 1152/4885MAPT 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.