Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.39 |
| ▸ | MDM4 | O15151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697534 | 0.85 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL697276 | 0.84 | CYP19A1 (0.41) | CYP19A1MDM2F2RL1 | |
| SCHEMBL705114 | 0.84 | CYP19A1 (0.42) | CYP19A1MDM2 | |
| SCHEMBL697717 | 0.82 | CYP19A1 (0.51) | CYP19A1MDM2F2RL1 | |
| SCHEMBL5924568 | 0.81 | CYP19A1 (0.49) | CYP19A1MDM2NR3C1F2RL1 | |
| SCHEMBL697087 | 0.81 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL6302051 | 0.81 | CYP19A1 (0.47) | CYP19A1 | |
| SCHEMBL696425 | 0.80 | KCNH2 (0.42) | CYP19A1 | |
| SCHEMBL697231 | 0.79 | CYP19A1 (0.38) | CYP19A1MDM2F2RL1 | |
| SCHEMBL697864 | 0.79 | CYP19A1 (0.48) | CYP19A1MDM2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |