Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697313 | 0.85 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL697452 | 0.84 | CYP19A1 (0.49) | CYP19A1MEN1KMT2ATAAR1CES2 | |
| SCHEMBL705114 | 0.84 | CYP19A1 (0.42) | CYP19A1MEN1KMT2AKMOCYP2C8 | |
| SCHEMBL696425 | 0.82 | KCNH2 (0.42) | CYP19A1 | |
| SCHEMBL697717 | 0.82 | CYP19A1 (0.51) | CYP19A1MEN1KMT2AIDO1TAAR1 | |
| SCHEMBL11536872 | 0.81 | CYP19A1 (0.54) | CYP19A1MEN1KMT2AKMOCYP2D6 | |
| SCHEMBL6302051 | 0.81 | CYP19A1 (0.47) | CYP19A1MEN1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL697087 | 0.81 | CYP19A1 (0.47) | CYP19A1MEN1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL27733475 | 0.79 | CYP19A1 (0.38) | CYP19A1ALDH1A1 | |
| SCHEMBL696829 | 0.78 | TAAR1 (0.44) | CYP19A1CYP2D6CYP2C9TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |