Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705114 | 0.84 | CYP19A1 (0.42) | CYP19A1TAAR1MDM2CNR2CYP3A4 | |
| SCHEMBL697313 | 0.82 | CYP19A1 (0.41) | CYP19A1MDM2F2RL1 | |
| SCHEMBL697534 | 0.82 | CYP19A1 (0.41) | CYP19A1TAAR1MEN1KMT2AIDO1 | |
| SCHEMBL11533065 | 0.81 | CYP19A1 (0.66) | CYP19A1TAAR1RORCIDO1 | |
| SCHEMBL697087 | 0.81 | CYP19A1 (0.47) | CYP19A1TAAR1CYP3A4MEN1KMT2A | |
| SCHEMBL6302051 | 0.81 | CYP19A1 (0.47) | CYP19A1TAAR1CYP3A4MEN1KMT2A | |
| SCHEMBL698661 | 0.81 | CYP19A1 (0.53) | CYP19A1MDM2ADRA2AADRA2CADRA1D | |
| SCHEMBL697370 | 0.79 | CYP19A1 (0.51) | CYP19A1MDM2ADRA2AADRA2CADRA1D | |
| SCHEMBL27733475 | 0.79 | CYP19A1 (0.38) | CYP19A1MDM2CYP3A4 | |
| SCHEMBL699118 | 0.78 | CYP19A1 (0.50) | CYP19A1MDM2CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |