SCHEMBL6973150

SCHEMBL6973150

CC(=O)NC[C@H]1CN(c2cccc3c2N(C(=O)CO)[C@H](C)CC3)C(=O)O1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.42
MAOB P27338 2/20 0.42
LMNA P02545 1/20 0.42
PTGS1 P23219 1/20 0.42
CALML3 P27482 1/20 0.42
SDHA P31040 1/20 0.42
MTNR1A P48039 6/20 0.38
F10 P00742 2/20 0.38
MTNR1B P49286 1/20 0.37
ABCB11 O95342 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965059 0.86 MAOA (0.43) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL6040275 0.81 MAOA (0.55) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL6973226 0.78 MAOA (0.37) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL6968403 0.75 MAOA (0.56) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL14069864 0.74 MAOA (0.53) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL6040246 0.74 MAOA (0.59) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL6965187 0.74 MAOA (0.59) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL6970806 0.74 MAOA (0.59) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL6854026 0.72 MAOA (0.53) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL3181066 0.72 MAOA (0.60) MAOAMAOBLMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181288-B1 BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT UPJOHN CO (US) 2003-07-30 EP claimed