Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CALML3 | P27482 | 1/20 | 0.37 |
| ▸ | SDHA | P31040 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 9/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965059 | 0.92 | MAOA (0.43) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6040470 | 0.81 | MAOB (0.49) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6973150 | 0.78 | MAOA (0.42) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6040829 | 0.75 | MAOB (0.52) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6040386 | 0.73 | MAOA (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6968441 | 0.73 | MAOA (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL7953617 | 0.72 | MAOB (0.58) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6974618 | 0.72 | MAOA (0.50) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6974624 | 0.72 | MAOA (0.50) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL6040490 | 0.72 | MAOB (0.48) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181288-B1 | BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT | UPJOHN CO (US) | 2003-07-30 | — | — | EP | claimed |