SCHEMBL6973258

SCHEMBL6973258

c1ccc(Sn2ccnc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
CYP11B1 P15538 5/20 0.41
CYP11B2 P19099 5/20 0.41
CYP19A1 P11511 5/20 0.41
MAPT P10636 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP2D6 P10635 1/20 0.41
TBXAS1 P24557 1/20 0.41
QPCT Q16769 1/20 0.41
CYP4Z1 Q86W10 1/20 0.41
QPCTL Q9NXS2 1/20 0.41
CYP17A1 P05093 5/20 0.41
USP2 O75604 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
TDP1 Q9NUW8 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL611405 0.82 CYP19A1 (0.54) MEN1KMT2ACYP19A1MAPTALDH1A1
SCHEMBL5609661 0.80 CYP19A1 (0.33) CYP3A4MEN1KMT2AALOX15TSHR
SCHEMBL5064961 0.71 CYP3A4 (0.50) CYP3A4ALOX15TSHRCYP11B1CYP11B2
SCHEMBL19468267 0.68 CYP3A4 (0.39) CYP3A4MEN1KMT2AALOX15TSHR
SCHEMBL8800965 0.67 CYP11B1 (0.55) CYP3A4TSHRCYP11B1CYP11B2CYP19A1
SCHEMBL27831756 0.67 ALDH1A1 (0.39) CYP3A4MEN1KMT2ACYP11B1CYP11B2
SCHEMBL4625690 0.66 NFKB1 (0.41) CYP3A4CYP11B1MAPTTBXAS1QPCT
SCHEMBL1859300 0.66 NFKB1 (0.41) CYP3A4CYP11B1MAPTTBXAS1QPCT
SCHEMBL27643754 0.66 QPCT (0.46) CYP3A4ALOX15CYP11B1CYP11B2CYP19A1
SCHEMBL7007424 0.66 CYP3A4 (0.69) CYP3A4MEN1KMT2AALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111631223-A Broad-spectrum bactericidal low-toxicity growth-promoting thiophanate-methyl metal compound and composition thereof 刘力 2020-09-08 CN claimed
CN-111559984-A Broad-spectrum sterilization low-toxicity low-residue growth promoting prothioconazole manganese zinc compound and composition thereof 刘力 2020-08-21 CN claimed
CN-111548293-A Broad-spectrum bactericidal low-toxicity low-residue growth-promoting thiophanate-manganese-zinc compound and composition thereof 刘力 2020-08-18 CN claimed
CN-111423472-A Broad-spectrum sterilization low-toxicity low-residue growth-promoting Thisen manganese zinc compound and composition thereof 刘力 2020-07-17 CN claimed
CN-111333594-A Broad-spectrum bactericidal low-toxicity low-residue phyllobius compound and composition thereof 刘力 2020-06-26 CN claimed
CN-111187234-A Broad-spectrum bactericidal pollution-free growth-promoting manganese thiazole compound and composition thereof 刘力 2020-05-22 CN claimed
CN-111138379-A Broad-spectrum bactericidal pollution-free growth-promoting thiazole manganese zinc compound and composition thereof 刘力 2020-05-12 CN claimed
CN-110881476-A High-efficiency broad-spectrum low-toxicity environment-friendly agricultural new compound and composition thereof 刘力 2020-03-17 CN claimed
CN-121378146-A Method for preparing phenylthioimidazole by taking m-dichlorobenzene as raw material 江苏宝众宝达药业股份有限公司 2026-01-23 CN disclosed
CN-121378146-A Method for preparing phenylthioimidazole by taking m-dichlorobenzene as raw material 江苏宝众宝达药业股份有限公司 2026-01-23 CN disclosed
CN-117797144-A Fenbendazole solid dispersion and preparation method thereof 浙江汰泽医药科技有限公司 2024-04-02 CN disclosed
CN-116893229-A Quantitative detection method for peroxide and organic peroxide in water-insoluble system 陕西汉江药业集团股份有限公司 2023-10-17 CN disclosed
CN-116496192-B Preparation method of 4-phenylthio-1, 2-phenylenediamine 山东国邦药业有限公司 2023-09-19 CN disclosed
CN-116496181-B Cyclization agent N- (methoxycarbonyl) iminomethyl carbonate and method for synthesizing fenbendazole by using same 山东国邦药业有限公司 2023-09-01 CN disclosed
CN-1656109-A Non-nucleoside reverse transcriptase inhibitors GILEAD SCIENCES INC (US) 2005-08-17 CN disclosed
EP-0786455-B1 IMIDAZOLE DERIVATIVE SHIONOGI & CO (JP) 2003-12-03 EP disclosed
US-6147097-A METHOD FOR TREATING AIDS SHIONOGI & CO., LTD. (JP) 2000-11-14 US disclosed
US-5910506-A IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC SHIONOGI & CO., LTD. (JP) 1999-06-08 US disclosed
EP-0786455-A1 IMIDAZOLE DERIVATIVE SHIONOGI & CO., LTD. (JP) 1997-07-30 EP disclosed
US-4402960-A Antiinflammatory imidazole derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1983-09-06 US disclosed