Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727180 | 0.85 | PPARG (0.57) | PTPN1PPARGPPARAFFAR1MAPT | |
| SCHEMBL6584128 | 0.84 | PPARG (0.62) | PPARGMTNR1AMTNR1BPPARAAPP | |
| SCHEMBL6967418 | 0.84 | ALDH1A1 (0.47) | PTPN1PPARGMTNR1AMTNR1BPPARA | |
| SCHEMBL8341338 | 0.83 | PPARG (0.41) | PPARGMTNR1AMTNR1BPPARAAPP | |
| SCHEMBL8888384 | 0.83 | PPARG (0.44) | PPARGMTNR1AMTNR1BPPARAAPP | |
| SCHEMBL6969220 | 0.81 | PTPN1 (0.44) | PTPN1PPARGMTNR1AMTNR1BPPARA | |
| SCHEMBL8801421 | 0.80 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL4847898 | 0.78 | NPC1 (0.48) | GAAF2RL3MEN1KMT2A | |
| SCHEMBL6960498 | 0.78 | HDAC1 (0.45) | PTPN1PPARGMTNR1AMTNR1BAPP | |
| SCHEMBL6973190 | 0.77 | PTPN1 (0.43) | PTPN1PPARGMTNR1AMTNR1BAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783496-B9 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0783496-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-26 | — | — | EP | disclosed |