Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975541 | 0.92 | KDM4E (0.51) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL11241868 | 0.87 | ALDH1A1 (0.46) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL3142775 | 0.83 | ALDH1A1 (0.57) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL9140339 | 0.78 | MAPT (0.58) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL1865789 | 0.78 | MAPT (0.50) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL25569790 | 0.78 | HPGD (0.47) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL9144382 | 0.78 | RARB (0.51) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL9144389 | 0.78 | RARB (0.51) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL10443684 | 0.76 | CA12 (0.57) | MAPTKDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL27534622 | 0.76 | ALDH1A1 (0.39) | MAPTKDM4ELMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044973-B1 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | AMERICAN CYANAMID CO (US) | 2003-10-08 | — | — | EP | disclosed |
| CN-1310717-A | Process for dehalogenation of thiochroman and thiochromene derivatives | AMERICAN CYANAMID CO (US) | 2001-08-29 | — | — | CN | disclosed |
| US-6180797-B1 | MULTISTAGE REACTION AND HYDROLYSIS TO FORM HERBICIDES | AMERICAN CYANAMID CO. | 2001-01-30 | — | — | US | disclosed |
| EP-1044973-A2 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | American Cyanamid Company (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000059898-A2 | PROCESS FOR THE DEHALOGENATION OF THIOCHROMAN AND DIHYDROBENZOTHIOPHENE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |