Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973452 | 0.92 | MAPT (0.60) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL27534622 | 0.85 | ALDH1A1 (0.39) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL9140339 | 0.84 | MAPT (0.58) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL9144382 | 0.83 | RARB (0.51) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL9144389 | 0.83 | RARB (0.51) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL28747049 | 0.82 | ALDH1A1 (0.40) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL10693463 | 0.81 | ATM (0.42) | KDM4EMAPTALDH1A1NPC1HSD17B10 | |
| SCHEMBL4694745 | 0.79 | MAPT (0.47) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL457941 | 0.79 | CA12 (0.56) | KDM4EMAPTALDH1A1NPC1LMNA | |
| SCHEMBL16329478 | 0.79 | ALDH1A1 (0.56) | KDM4EMAPTALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044973-B1 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | AMERICAN CYANAMID CO (US) | 2003-10-08 | — | — | EP | disclosed |
| US-6180797-B1 | MULTISTAGE REACTION AND HYDROLYSIS TO FORM HERBICIDES | AMERICAN CYANAMID CO. | 2001-01-30 | — | — | US | disclosed |
| EP-1044973-A2 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | American Cyanamid Company (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000059898-A2 | PROCESS FOR THE DEHALOGENATION OF THIOCHROMAN AND DIHYDROBENZOTHIOPHENE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |