Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964470 | 1.00 | CFTR (0.42) | CFTRS1PR3CYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL6973761 | 0.90 | CFTR (0.44) | CFTRS1PR3CYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL6972288 | 0.86 | PDE4A (0.37) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6972294 | 0.86 | PDE4A (0.37) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6973783 | 0.86 | SMN1; SMN2 (0.38) | CFTRCYP1A2L3MBTL1POLBALDH1A1 | |
| SCHEMBL6973778 | 0.86 | SMN1; SMN2 (0.38) | CFTRCYP1A2L3MBTL1POLBALDH1A1 | |
| SCHEMBL7085317 | 0.86 | ALDH1A1 (0.34) | S1PR3CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL7085318 | 0.86 | ALDH1A1 (0.34) | S1PR3CYP1A2ALDH1A1NPC1RAB9A | |
| SCHEMBL6969251 | 0.85 | GRIN1 (0.38) | S1PR3ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6971733 | 0.85 | GRM5 (0.35) | S1PR3CYP1A2CYP3A4L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |