Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703921 | 1.00 | PTGER4 (0.49) | PTGER4PTGER3PTGER2P2RX7KMT2A | |
| SCHEMBL6791024 | 0.87 | P2RX7 (0.41) | PTGER4PTGER3PTGER2P2RX7 | |
| SCHEMBL4994863 | 0.84 | PTGER4 (0.49) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6713022 | 0.83 | PTGER4 (0.50) | PTGER4PTGER3PTGER2P2RX7 | |
| SCHEMBL4994708 | 0.77 | PTGER4 (0.58) | PTGER4PTGER3PTGER2P2RX7 | |
| SCHEMBL6688084 | 0.77 | PTGER4 (0.78) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6688089 | 0.77 | PTGER4 (0.78) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6697546 | 0.76 | PTGER4 (0.60) | PTGER4PTGER3PTGER2P2RX7 | |
| SCHEMBL6688114 | 0.76 | PTGER4 (0.80) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6710589 | 0.76 | PTGER4 (0.60) | PTGER4PTGER3PTGER2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110949-B1 | EP4 receptor selective agonists in the treatment of osteoporosis | PFIZER PROD INC (US) | 2003-09-24 | — | — | EP | disclosed |