Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974141 | 1.00 | KDM4E (0.51) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL5426275 | 0.85 | HTR2A (0.60) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL5426277 | 0.85 | HTR2A (0.60) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL14496791 | 0.82 | HTR2A (0.51) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL6976076 | 0.82 | MEN1 (0.51) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL6976079 | 0.82 | MEN1 (0.51) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL17707693 | 0.81 | MEN1 (0.57) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL4267038 | 0.81 | MEN1 (0.57) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL12507269 | 0.81 | KCNH2 (0.50) | KDM4EMEN1KMT2AHTR2ANR1I2 | |
| SCHEMBL8973646 | 0.81 | KCNH2 (0.50) | KDM4EMEN1KMT2AHTR2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |