Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 19/20 | 0.65 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975739 | 0.88 | BDKRB2 (0.70) | BDKRB2RORC | |
| SCHEMBL7749582 | 0.88 | BDKRB2 (0.51) | BDKRB2 | |
| Hydrochloric Acid SCHEMBL6958840 | 0.86 | BDKRB2 (0.69) | BDKRB2RORC | |
| SCHEMBL6643996 | 0.86 | BDKRB2 (0.58) | BDKRB2 | |
| Phthalimide SCHEMBL6974162 | 0.86 | BDKRB2 (0.61) | BDKRB2RORC | |
| SCHEMBL6638337 | 0.86 | BDKRB2 (0.62) | BDKRB2 | |
| SCHEMBL6974081 | 0.86 | BDKRB2 (0.78) | BDKRB2RORC | |
| SCHEMBL6642693 | 0.86 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL6643523 | 0.85 | BDKRB2 (0.63) | BDKRB2 | |
| SCHEMBL6974368 | 0.84 | BDKRB2 (0.79) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900203-B1 | QUINOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6083959-A | BRADYKININ ANTAGONISTS; FOR THE PREVENTION AND/OR THE TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES SUCH AS ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |